BDBM50499271 CHEMBL3736245

SMILES COc1ccc(cc1)C1CC(=NN1c1ccc(cc1)C(O)=O)c1ccc(cc1)S(C)(=O)=O

InChI Key InChIKey=NIGPWMZMRKTFGZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50499271   

TargetProstaglandin G/H synthase 2(Human)
Beni-Suef University

Curated by ChEMBL
LigandPNGBDBM50499271(CHEMBL3736245)
Affinity DataIC50: 2.17E+3nMAssay Description:Inhibition of human recombinant COX-2 preincubated for 2 mins prior to arachidonic acid addition by enzyme immuno assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Beni-Suef University

Curated by ChEMBL
LigandPNGBDBM50499271(CHEMBL3736245)
Affinity DataIC50: 6.60E+3nMAssay Description:Inhibition of ovine COX-1 preincubated for 2 mins prior to arachidonic acid addition by enzyme immuno assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed