BDBM50499373 CHEMBL3735090

SMILES CC(=O)N1CCN(CC1)c1ccc(Nc2c(cnc3ccc(cc23)-c2cnc3ccccc3c2)C(N)=O)cc1C(F)(F)F

InChI Key InChIKey=ZXCABQMRPVVKSS-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50499373   

TargetSerine/threonine-protein kinase mTOR(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50499373(CHEMBL3735090)
Affinity DataIC50: 31nMAssay Description:Inhibition of mTOR (unknown origin) using ULight-4E-BP1 peptide as substrate after 1 hr by lance ultra assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
LigandPNGBDBM50499373(CHEMBL3735090)
Affinity DataIC50: 939nMAssay Description:Inhibition of PI3Kgamma (unknown origin) after 1 hr by ADP-Glo Luminescent assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
LigandPNGBDBM50499373(CHEMBL3735090)
Affinity DataIC50: 2.43E+3nMAssay Description:Inhibition of PI3Kalpha (unknown origin) after 1 hr by Kinase-Glo Luminescent assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
LigandPNGBDBM50499373(CHEMBL3735090)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of PI3Kbeta (unknown origin) after 1 hr by ADP-Glo Luminescent assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
LigandPNGBDBM50499373(CHEMBL3735090)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of PI3Kdelta (unknown origin) after 1 hr by ADP-Glo Luminescent assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed