BDBM50499544 CHEMBL3740127

SMILES Fc1ccc2[nH]c(=S)n(Nc3ncc(cc3Cl)C(F)(F)F)c(=O)c2c1

InChI Key InChIKey=PWMKLPHWIKBOOX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50499544   

TargetMyeloperoxidase(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50499544(CHEMBL3740127)
Affinity DataIC50: 100nMAssay Description:Inhibition of human recombinant myeloperoxidase by amplex red assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetXanthine dehydrogenase/oxidase(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50499544(CHEMBL3740127)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of xanthine oxidase (unknown origin) assessed as superoxide generation measured for 20 mins by luminescence analysis using 50 uM xanthine ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed