BDBM50499869 CHEMBL3742140

SMILES N#CCN(CCN1CCN(c2ccc3cc[nH]c3c2Cl)CC1)[C@H]1CCc2nc(N)sc2C1

InChI Key InChIKey=XNSOJCJPLUSJAA-UHFFFAOYSA-N

Data  2 KI  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50499869   

TargetD(3) dopamine receptor(Rat)
Wayne State University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50499869BDBM50499869(CHEMBL3742140)
Affinity DataKi:  0.145nMAssay Description:Displacement of [3H]Spiroperidol from cloned rat dopamine D3 receptor expressed in HEK293 cells by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
Wayne State University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50499869BDBM50499869(CHEMBL3742140)
Affinity DataEC50:  0.840nMAssay Description:Agonist activity at human D3 receptor expressed in CHO cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Wayne State University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50499869BDBM50499869(CHEMBL3742140)
Affinity DataEC50:  39nMAssay Description:Agonist activity at human D2 receptor expressed in CHO cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Wayne State University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50499869BDBM50499869(CHEMBL3742140)
Affinity DataKi:  172nMAssay Description:Displacement of [3H]Spiroperidol from cloned rat dopamine D2L receptor expressed in HEK293 cells by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed