BDBM50499956 CHEMBL3741710

SMILES Cc1cccc(C)c1NC(=O)c1cc(nc2ccccc12)-c1ccccc1

InChI Key InChIKey=AKCQWCNDUPKMFE-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50499956   

TargetProstaglandin E2 receptor EP4 subtype(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50499956(CHEMBL3741710)
Affinity DataIC50: 128nMAssay Description:Antagonist activity at human EP4 receptor in HEK293 cells assessed as inhibition of PGE2-induced cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP4 subtype(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50499956(CHEMBL3741710)
Affinity DataKi:  512nMAssay Description:Antagonist activity at human EP4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP4 subtype(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50499956(CHEMBL3741710)
Affinity DataIC50: 3.00E+4nMAssay Description:Antagonist activity at EP4 receptor in human whole blood assessed as reversal of inhibition of PGE2 mediated LPS-induced TNF alpha production pretrea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed