BDBM50500479 CHEMBL3747356

SMILES [H][C@@]12CN(C[C@]1([H])[C@H]2c1nnco1)C(=O)c1ccc(C[C@@H]2CC[C@@]([H])(N2)[C@H](O)c2ccccc2)cc1

InChI Key InChIKey=XIZLMQMPAXXTME-UHFFFAOYSA-N

Data  3 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50500479   

TargetBeta-3 adrenergic receptor(Human)
Merck And

Curated by ChEMBL
LigandPNGBDBM50500479(CHEMBL3747356)
Affinity DataEC50:  1.70nMAssay Description:Agonist activity at human beta-3 adrenergic receptor expressed in CHO cells assessed as reduction in cAMP level after 30 mins by LANCE TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetBeta-1 adrenergic receptor(Human)
Merck And

Curated by ChEMBL
LigandPNGBDBM50500479(CHEMBL3747356)
Affinity DataIC50: 2.00E+4nMAssay Description:Displacement of [125I]CYP from human beta-1 adrenergic receptor expressed in CHO cell membrane after 1 hr by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Human)
Merck And

Curated by ChEMBL
LigandPNGBDBM50500479(CHEMBL3747356)
Affinity DataIC50: 2.00E+4nMAssay Description:Displacement of [125I]CYP from human beta-2 adrenergic receptor expressed in CHO cell membrane after 1 hr by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
LigandPNGBDBM50500479(CHEMBL3747356)
Affinity DataIC50: 5.50E+4nMAssay Description:Inhibition of human ERG by IKr binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed