BDBM50500497 CHEMBL3746208

SMILES N#Cc1cccc(C(=O)Nc2ncc(-c3nc4ccccc4[nH]3)s2)c1

InChI Key InChIKey=RTHSEVGWSBDFFR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50500497   

LigandChemical structure of BindingDB Monomer ID 50500497BDBM50500497(CHEMBL3746208)
Affinity DataIC50: 110nMAssay Description:Inhibition of human recombinant PDE10A using cAMP as substrate preincubated for 20 mins followed by substrate addition measured after 2 hrs by FRET a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Human)
AstraZeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50500497BDBM50500497(CHEMBL3746208)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant PDE2A using cAMP as substrate preincubated for 20 mins followed by substrate addition measured after 2 hrs by FRET as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed