BDBM50500503 CHEMBL3746615

SMILES Cc1c(Cl)cccc1C(=O)Nc1cc(-c2nc3ccccc3[nH]2)[nH]n1

InChI Key InChIKey=OSGMULIPPPBILX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50500503   

LigandChemical structure of BindingDB Monomer ID 50500503BDBM50500503(CHEMBL3746615)
Affinity DataIC50: 100nMAssay Description:Inhibition of human recombinant PDE10A using cAMP as substrate preincubated for 20 mins followed by substrate addition measured after 2 hrs by FRET a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Human)
AstraZeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50500503BDBM50500503(CHEMBL3746615)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant PDE2A using cAMP as substrate preincubated for 20 mins followed by substrate addition measured after 2 hrs by FRET as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed