BDBM50500540 CHEMBL3747767

SMILES [H][C@@]12Cc3c([nH]c4ccccc34)[C@H](CC(C)C)N1C(=O)[C@H](CCC(O)=O)NC2=O

InChI Key InChIKey=ZABODVDQHQNZFF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50500540   

TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Human)
Takeda Pharmaceuticals International

Curated by ChEMBL
LigandPNGBDBM50500540(CHEMBL3747767)
Affinity DataIC50: 230nMAssay Description:Inhibition of BCRP in human Caco2 cells using 3H-Estron-3-sulfate as substrate assessed as Ko143 IC50 measured at 30 to 120 mins by microplate scinti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Human)
Takeda Pharmaceuticals International

Curated by ChEMBL
LigandPNGBDBM50500540(CHEMBL3747767)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of BCRP in human Caco2 cells using 3H-Estron-3-sulfate as substrate measured at 30 to 120 mins by microplate scintillation and luminescenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed