BDBM50500716 CHEMBL3752419

SMILES COc1ccc(cc1)-c1ccc(cc1)S(=O)(=O)N[C@H](CCCCCF)P(O)(O)=O

InChI Key InChIKey=CZWJAEJHLBICAX-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50500716   

TargetNeutrophil collagenase(Human)
Westf£Lische Wilhelms-Universit£T

Curated by ChEMBL
LigandPNGBDBM50500716(CHEMBL3752419)
Affinity DataIC50: 42nMAssay Description:Inhibition of MMP8 (unknown origin) using (7-methoxycoumarin-4-yl) acetyl pro-Leu-Gly-Leu-[3-(2,4-dinitrophenyl)-L-2,3-diamino-propionyl]-Ala-Arg-NH2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Westf£Lische Wilhelms-Universit£T

Curated by ChEMBL
LigandPNGBDBM50500716(CHEMBL3752419)
Affinity DataIC50: 94nMAssay Description:Inhibition of MMP13 (unknown origin) using (7-methoxycoumarin-4-yl) acetyl pro-Leu-Gly-Leu-[3-(2,4-dinitrophenyl)-L-2,3-diamino-propionyl]-Ala-Arg-NH...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Westf£Lische Wilhelms-Universit£T

Curated by ChEMBL
LigandPNGBDBM50500716(CHEMBL3752419)
Affinity DataIC50: 791nMAssay Description:Inhibition of human MMP2 using (7-methoxycoumarin-4-yl) acetyl pro-Leu-Gly-Leu-[3-(2,4-dinitrophenyl)-L-2,3-diamino-propionyl]-Ala-Arg-NH2 as substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Westf£Lische Wilhelms-Universit£T

Curated by ChEMBL
LigandPNGBDBM50500716(CHEMBL3752419)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human MMP9 using (7-methoxycoumarin-4-yl) acetyl pro-Leu-Gly-Leu-[3-(2,4-dinitrophenyl)-L-2,3-diamino-propionyl]-Ala-Arg-NH2 as substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed