BDBM50500916 CHEMBL3800314

SMILES COCCN(Cc1cc(cc2c1oc(cc2=O)N1CCOCC1)C(=O)N(C)C)c1cc(F)cc(F)c1

InChI Key InChIKey=IJKVNSWSGUDBLV-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50500916   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Human)
Astrazeneca

Curated by ChEMBL

LigandBDBM50500916(CHEMBL3800314)Copy SMILESCopy InChI

Affinity DataIC50: 17nMAssay Description:Inhibition of PI3Kbeta in PTEN deficient human MDA-MB-468 cells assessed as inhibition of AKT phosphorylation at Ser-473 residue after 2 hrs by plate...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
9/4/2020
Entry Details Article
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