BDBM50501845 CHEMBL4571844

SMILES Cc1nnc2CN(CCn12)C(=O)c1ccc(\C=C2/Oc3c(cccc3C(N)=O)C2=O)cc1

InChI Key InChIKey=GTZILCFFHHBZOR-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50501845   

TargetPoly [ADP-ribose] polymerase 2(Human)
St. John'S University

Curated by ChEMBL
LigandPNGBDBM50501845(CHEMBL4571844)
Affinity DataIC50: 10nMAssay Description:Inhibition of human N-terminal GST-tagged PARP2 (2 to 583 residues) expressed in baculovirus infected Sf9 insect cells using histone as substrate mea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
St. John'S University

Curated by ChEMBL
LigandPNGBDBM50501845(CHEMBL4571844)
Affinity DataIC50: 79nMAssay Description:Inhibition of human full-length N-terminal GST-tagged PARP1 expressed in baculovirus infected Sf9 insect cells using histone as substrate measured af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
St. John'S University

Curated by ChEMBL
LigandPNGBDBM50501845(CHEMBL4571844)
Affinity DataIC50: 81nMAssay Description:Inhibition of human full-length N-terminal GST-tagged PARP1 expressed in baculovirus infected Sf9 insect cells using histone as substrate measured af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed