BDBM50501940 CHEMBL4462680

SMILES CN[C@@H](C)C(=O)N[C@@H](CCc1ccc(OS(F)(=O)=O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(N)=O

InChI Key InChIKey=OMGLGDZBHKICGG-UHFFFAOYSA-N

Data  13 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 13 hits for monomerid = 50501940   

TargetE3 ubiquitin-protein ligase XIAP(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50501940(CHEMBL4462680)
Affinity DataIC50: 12nMAssay Description:Covalent binding affinity to N-terminal His tagged recombinant human XIAP-BIR3 domain (253 to 347 residues) expressed in Escherichia coli BL21(DE3) c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase XIAP(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50501940(CHEMBL4462680)
Affinity DataIC50: 70nMAssay Description:Displacement of biotinylated AVPF from N-terminal His tagged recombinant human XIAP-BIR3 Lys311Ala mutant expressed in Escherichia coli BL21(DE3) cel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase XIAP(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50501940(CHEMBL4462680)
Affinity DataIC50: 70nMAssay Description:Displacement of biotinylated AVPF from N-terminal His tagged recombinant human XIAP-BIR3 Lys311Ala mutant expressed in Escherichia coli BL21(DE3) cel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase XIAP(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50501940(CHEMBL4462680)
Affinity DataIC50: 80nMAssay Description:Displacement of biotinylated AVPF from N-terminal His tagged recombinant human XIAP-BIR3 Lys311Tyr mutant expressed in Escherichia coli BL21(DE3) cel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase XIAP(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50501940(CHEMBL4462680)
Affinity DataIC50: 86nMAssay Description:Displacement of biotinylated AVPF from N-terminal His tagged recombinant human XIAP-BIR3 Lys311Tyr mutant expressed in Escherichia coli BL21(DE3) cel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase XIAP(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50501940(CHEMBL4462680)
Affinity DataIC50: 90nMAssay Description:Displacement of biotinylated AVPF from N-terminal His tagged recombinant human XIAP-BIR3 domain (253 to 347 residues) expressed in Escherichia coli B...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase XIAP(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50501940(CHEMBL4462680)
Affinity DataIC50: 98nMAssay Description:Displacement of biotinylated AVPF from N-terminal His tagged recombinant human XIAP-BIR3 Lys311His mutant expressed in Escherichia coli BL21(DE3) cel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase XIAP(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50501940(CHEMBL4462680)
Affinity DataIC50: 126nMAssay Description:Displacement of biotinylated AVPF from N-terminal His tagged recombinant human XIAP-BIR3 Lys311His mutant expressed in Escherichia coli BL21(DE3) cel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase XIAP(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50501940(CHEMBL4462680)
Affinity DataIC50: 165nMAssay Description:Displacement of biotinylated AVPF from N-terminal His tagged recombinant human XIAP-BIR3 Lys311Thr mutant expressed in Escherichia coli BL21(DE3) cel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase XIAP(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50501940(CHEMBL4462680)
Affinity DataIC50: 180nMAssay Description:Displacement of biotinylated AVPF from N-terminal His tagged recombinant human XIAP-BIR3 Lys311Thr mutant expressed in Escherichia coli BL21(DE3) cel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase XIAP(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50501940(CHEMBL4462680)
Affinity DataIC50: 237nMAssay Description:Displacement of biotinylated AVPF from N-terminal His tagged recombinant human XIAP-BIR3 Lys311Ser mutant expressed in Escherichia coli BL21(DE3) cel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase XIAP(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50501940(CHEMBL4462680)
Affinity DataIC50: 250nMAssay Description:Displacement of biotinylated AVPF from N-terminal His tagged recombinant human XIAP-BIR3 Lys311Ser mutant expressed in Escherichia coli BL21(DE3) cel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase XIAP(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50501940(CHEMBL4462680)
Affinity DataIC50: 2.00E+3nMAssay Description:Displacement of biotinylated AVPF from N-terminal His tagged recombinant human XIAP-BIR3 domain (253 to 347 residues) expressed in Escherichia coli B...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed