BDBM50502340 CHEMBL4554676

SMILES CN1c2ccccc2CC[C@H](NC(=O)c2n[nH]c(Cc3ccccc3)n2)C1=O

InChI Key InChIKey=DWEYACIOYHILCZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50502340   

LigandPNGBDBM50502340(CHEMBL4554676)
Affinity DataIC50: 5nMAssay Description:Inhibition of pDEST8HisGSTTev-tagged human RIP1 (1 to 375 residues) expressed in baculovirus infected insect cells preincubated with enzyme for 1 hr ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed
LigandPNGBDBM50502340(CHEMBL4554676)
Affinity DataIC50: 10nMAssay Description:Inhibition of RIP1 in human U937 cells assessed as reduction in necroptosis incubated for 24 hrs by cell titer-glo luminescent cell viability assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed