BDBM50503028 CHEMBL4464351

SMILES COc1cc(\C=C\C(=O)c2sc(NC(=O)c3ccccc3)nc2C)cc(OC)c1OC

InChI Key InChIKey=OXMFCMQBRXSYGF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50503028   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
National Institute of Pharmaceutical Education and Research

Curated by ChEMBL
LigandPNGBDBM50503028(CHEMBL4464351)
Affinity DataIC50: 70nMAssay Description:Inhibition of 5-LOX (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
National Institute of Pharmaceutical Education and Research

Curated by ChEMBL
LigandPNGBDBM50503028(CHEMBL4464351)
Affinity DataIC50: 70nMAssay Description:Inhibition of human recombinant 5-LOX expressed in Escherichia coli BL21 assessed as conversion of arachidonic acid to 5-HPETE using arachidonic acid...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed