BDBM50503219 CHEMBL4463029

SMILES Cc1ccc(Nc2nc3ncn(-c4c(C)cccc4Cl)c(=O)c3s2)cc1

InChI Key InChIKey=OQWFSIROIGDQSN-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50503219   

TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Peking University

Curated by ChEMBL
LigandPNGBDBM50503219(CHEMBL4463029)
Affinity DataEC50:  8.45E+3nMAssay Description:Positive allosteric modulation activity at alpha7 nAChR (unknown origin) expressed in Xenopus laevis oocytes assessed as increase in acetylcholine-in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Peking University

Curated by ChEMBL
LigandPNGBDBM50503219(CHEMBL4463029)
Affinity DataEC50:  8.45E+3nMAssay Description:Positive allosteric modulation of human alpha7 nAChR expressed in Xenopus laevis oocytes assessed as increase in acetylcholine-induced channel curren...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed