BDBM50503342 CHEMBL4436074

SMILES CS(=O)(=O)c1ccc(CN2CCN(CC2)C(=O)OC(C(F)(F)F)C(F)(F)F)c(c1)N1CCCC1

InChI Key InChIKey=SPTBSRXDWQDJKA-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50503342   

TargetMonoglyceride lipase(Human)
Abide Therapeutics

Curated by ChEMBL
LigandPNGBDBM50503342(CHEMBL4436074)
Affinity DataIC50: 11nMAssay Description:Inhibition of MGLL derived from human PC3 cell lysates preincubated for 30 mins followed by JW912 addition after 30 mins by gel-based ABPP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetMonoacylglycerol lipase ABHD6(Human)
Abide Therapeutics

Curated by ChEMBL
LigandPNGBDBM50503342(CHEMBL4436074)
Affinity DataIC50: 99nMAssay Description:Inhibition of ABHD6 derived from human PC3 cell lysates preincubated for 30 mins followed by JW912 addition after 30 mins by gel-based ABPP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetPlatelet-activating factor acetylhydrolase(Human)
Abide Therapeutics

Curated by ChEMBL
LigandPNGBDBM50503342(CHEMBL4436074)
Affinity DataIC50: 430nMAssay Description:Inhibition of PLA2G7 derived from human PC3 cell lysates preincubated for 30 mins followed by JW912 addition after 30 mins by gel-based ABPP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed