BDBM50503345 CHEMBL4550205

SMILES FC(F)(F)C(OC(=O)N1CCN(Cc2ccc(cc2N2CCCCC2)C(F)(F)F)CC1)C(F)(F)F

InChI Key InChIKey=BYENLAAWZDJLPX-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50503345   

TargetMonoglyceride lipase(Human)
Abide Therapeutics

Curated by ChEMBL
LigandPNGBDBM50503345(CHEMBL4550205)
Affinity DataIC50: 17nMAssay Description:Inhibition of MGLL derived from human PC3 cell lysates preincubated for 30 mins followed by JW912 addition after 30 mins by gel-based ABPP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetMonoglyceride lipase(Mouse)
Abide Therapeutics

Curated by ChEMBL
LigandPNGBDBM50503345(CHEMBL4550205)
Affinity DataIC50: 130nMAssay Description:Inhibition of MGLL derived from mouse brain homogenates preincubated for 30 mins followed by JW912 addition after 30 mins by gel-based ABPP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetMonoacylglycerol lipase ABHD6(Human)
Abide Therapeutics

Curated by ChEMBL
LigandPNGBDBM50503345(CHEMBL4550205)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of ABHD6 derived from human PC3 cell lysates preincubated for 30 mins followed by JW912 addition after 30 mins by gel-based ABPP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetPlatelet-activating factor acetylhydrolase(Human)
Abide Therapeutics

Curated by ChEMBL
LigandPNGBDBM50503345(CHEMBL4550205)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PLA2G7 derived from human PC3 cell lysates preincubated for 30 mins followed by JW912 addition after 30 mins by gel-based ABPP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed