BDBM50503447 CHEMBL4476352::US11274074, Comparative Example 3 [Chemical Formula 21]

SMILES COc1cccc(\C=N\NC(=O)COc2ccc(Cl)cc2C)c1

InChI Key InChIKey=YGKZOLZHIZHROR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50503447   

TargetAnoctamin-1(Human)
Industry-Academic Cooperation Foundation Yonsei University

US Patent
LigandPNGBDBM50503447(CHEMBL4476352 | US11274074, Comparative Example 3 ...)
Affinity DataIC50: 1.00E+5nMAssay Description:The method for inhibiting the expression of ANO1 (TMEM16A) of the present disclosure includes a step of inhibiting the expression of ANO1 (TMEM16A) i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/4/2022
Entry Details
US Patent

TargetAnoctamin-1(Human)
Industry-Academic Cooperation Foundation Yonsei University

US Patent
LigandPNGBDBM50503447(CHEMBL4476352 | US11274074, Comparative Example 3 ...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of YFP-fused ANO1 (unknown origin) expressed in FRT cells after 20 mins by fluorescence quenching methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed