BDBM50503977 CHEMBL4465902
SMILES CCCCN(Cc1ccc(cc1)C(=O)NO)C(=O)Nc1ccc(OCCCCCn2cc(CNc3cccc4C(=O)N(C5CCC(=O)NC5=O)C(=O)c34)nn2)cc1
InChI Key InChIKey=DQGQXFRCIYCGOE-UHFFFAOYSA-N
Data 8 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 8 hits for monomerid = 50503977
TargetHistone deacetylase 1(Homo sapiens (Human))
Institute of Biotechnology of The Czech Academy of Sciences
Curated by ChEMBL
Institute of Biotechnology of The Czech Academy of Sciences
Curated by ChEMBL
Affinity DataIC50: >300nMAssay Description:Inhibition of human N-terminal tagged human HDAC1 expressed in HEK293T/17 using Ac-Gly-Ala-[Ac-Lys]-AMC as substrate preincubated for 10 mins followe...More data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))
Institute of Biotechnology of The Czech Academy of Sciences
Curated by ChEMBL
Institute of Biotechnology of The Czech Academy of Sciences
Curated by ChEMBL
Affinity DataIC50: 8.70nMAssay Description:Inhibition of human N-terminal tagged human HDAC6 expressed in HEK293T/17 using Ac-Gly-Ala-[Ac-Lys]-AMC as substrate preincubated for 10 mins followe...More data for this Ligand-Target Pair
TargetHistone deacetylase 5(Homo sapiens (Human))
Institute of Biotechnology of The Czech Academy of Sciences
Curated by ChEMBL
Institute of Biotechnology of The Czech Academy of Sciences
Curated by ChEMBL
Affinity DataIC50: >300nMAssay Description:Inhibition of human N-terminal tagged human HDAC5 expressed in HEK293T/17 using Boc-[TFA-Lys]-AMC as substrate preincubated for 10 mins followed by s...More data for this Ligand-Target Pair
TargetHistone deacetylase 8(Homo sapiens (Human))
Institute of Biotechnology of The Czech Academy of Sciences
Curated by ChEMBL
Institute of Biotechnology of The Czech Academy of Sciences
Curated by ChEMBL
Affinity DataIC50: >300nMAssay Description:Inhibition of human N-terminal tagged human HDAC8 expressed in HEK293T/17 using Boc-[TFA-Lys]-AMC as substrate preincubated for 10 mins followed by s...More data for this Ligand-Target Pair
TargetHistone deacetylase 9(Homo sapiens (Human))
Institute of Biotechnology of The Czech Academy of Sciences
Curated by ChEMBL
Institute of Biotechnology of The Czech Academy of Sciences
Curated by ChEMBL
Affinity DataIC50: >300nMAssay Description:Inhibition of human N-terminal tagged human HDAC9 expressed in HEK293T/17 using Boc-[TFA-Lys]-AMC as substrate preincubated for 10 mins followed by s...More data for this Ligand-Target Pair
TargetHistone deacetylase 4(Homo sapiens (Human))
Institute of Biotechnology of The Czech Academy of Sciences
Curated by ChEMBL
Institute of Biotechnology of The Czech Academy of Sciences
Curated by ChEMBL
Affinity DataIC50: >300nMAssay Description:Inhibition of human N-terminal tagged human HDAC4 expressed in HEK293T/17 using Boc-[TFA-Lys]-AMC as substrate preincubated for 10 mins followed by s...More data for this Ligand-Target Pair
TargetHistone deacetylase 11(Homo sapiens (Human))
Institute of Biotechnology of The Czech Academy of Sciences
Curated by ChEMBL
Institute of Biotechnology of The Czech Academy of Sciences
Curated by ChEMBL
Affinity DataIC50: >300nMAssay Description:Inhibition of human N-terminal tagged human HDAC11 expressed in HEK293T/17 using Boc-[TFA-Lys]-AMC as substrate preincubated for 10 mins followed by ...More data for this Ligand-Target Pair
TargetHistone deacetylase 7(Homo sapiens (Human))
Institute of Biotechnology of The Czech Academy of Sciences
Curated by ChEMBL
Institute of Biotechnology of The Czech Academy of Sciences
Curated by ChEMBL
Affinity DataIC50: >300nMAssay Description:Inhibition of human N-terminal tagged human HDAC7 expressed in HEK293T/17 using Boc-[TFA-Lys]-AMC as substrate preincubated for 10 mins followed by s...More data for this Ligand-Target Pair