BDBM50503985 CHEMBL4553989

SMILES Oc1cccc(c1)-c1nccc(n1)C12CC1COCC2

InChI Key InChIKey=AEIPQWQRUBJPGJ-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50503985   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Glaxosmithkline R&D

Curated by ChEMBL

LigandBDBM50503985(CHEMBL4553989)Copy SMILESCopy InChI

Affinity DataIC50: 3.98E+3nMAssay Description:Inhibition of PI3Kdelta (unknown origin) using PIP2 as substrate preincubated for 15 mins followed by substrate addition and measured after 1 hr by H...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
2/18/2021
Entry Details Article
Copy BDB DOIPubMed
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TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Glaxosmithkline R&D

Curated by ChEMBL

LigandBDBM50503985(CHEMBL4553989)Copy SMILESCopy InChI

Affinity DataIC50: 6.31E+3nMAssay Description:Inhibition of PI3Kalpha (unknown origin) using PIP2 as substrate preincubated for 15 mins followed by substrate addition and measured after 1 hr by H...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
2/18/2021
Entry Details Article
Copy BDB DOIPubMed
Copy reaction URL