BDBM50503994 CHEMBL4518889

SMILES [H][C@]12C[C@]1(CCOC2)c1cc(CS(C)(=O)=O)nc(n1)-c1ccc(NC(=O)NCC)cc1

InChI Key InChIKey=OVQKXJGLDKVMMI-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50503994   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Glaxosmithkline R&D

Curated by ChEMBL

LigandBDBM50503994(CHEMBL4518889)Copy SMILESCopy InChI

Affinity DataIC50: 7.94E+3nMAssay Description:Inhibition of PI3Kdelta (unknown origin) using PIP2 as substrate preincubated for 15 mins followed by substrate addition and measured after 1 hr by H...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
2/18/2021
Entry Details Article
Copy BDB DOIPubMed
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TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Glaxosmithkline R&D

Curated by ChEMBL

LigandBDBM50503994(CHEMBL4518889)Copy SMILESCopy InChI

Affinity DataIC50: 3.16E+4nMAssay Description:Inhibition of PI3Kalpha (unknown origin) using PIP2 as substrate preincubated for 15 mins followed by substrate addition and measured after 1 hr by H...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
2/18/2021
Entry Details Article
Copy BDB DOIPubMed
Copy reaction URL