BDBM50504024 CHEMBL4461925
SMILES Nc1n[nH]c(n1)N1CCC(CC1)N1CCOC[C@@H]1Cc1ccc(Cl)cc1
InChI Key InChIKey=WQWHBQYUWSARDT-INIZCTEOSA-N
Data 13 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 13 hits for monomerid = 50504024
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Oncoarendi Therapeutics
Curated by ChEMBL
Oncoarendi Therapeutics
Curated by ChEMBL
Affinity DataIC50: 3.90E+4nMAssay Description:Displacement of Tracer Red from human ERG by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Oncoarendi Therapeutics
Curated by ChEMBL
Oncoarendi Therapeutics
Curated by ChEMBL
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of human ERG expressed in CHO-K1 cells by automated Patch Clamp methodMore data for this Ligand-Target Pair
Affinity DataIC50: 48nMAssay Description:Inhibition of full-length C-terminal his-tagged human CHIT1 expressed in CHOK1 cells assessed as reduction in chitinolytic activity using 4-methylumb...More data for this Ligand-Target Pair
Affinity DataIC50: 22nMAssay Description:Inhibition of full-length C-terminal his-tagged human acidic mammalian chitinase expressed in CHOK1 cells assessed as reduction in chitinolytic activ...More data for this Ligand-Target Pair
Affinity DataIC50: 74nMAssay Description:Inhibition of full-length C-terminal his-tagged mouse CHIT1 expressed in CHO-K1 cells assessed as reduction in chitinolytic activity using 4-methylum...More data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Inhibition of full-length C-terminal his-tagged mouse acidic mammalian chitinase expressed in CHO-K1 cells assessed as reduction in chitinolytic acti...More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Oncoarendi Therapeutics
Curated by ChEMBL
Oncoarendi Therapeutics
Curated by ChEMBL
Affinity DataIC50: 3.90E+4nMAssay Description:Inhibition of tracer red binding to human ERG expressed in HEK293 cell membranes measured after 2 to 6 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Oncoarendi Therapeutics
Curated by ChEMBL
Oncoarendi Therapeutics
Curated by ChEMBL
Affinity DataIC50: 7.90E+3nMAssay Description:Displacement of [3H]DA from rat dopamine transporter after 15 mins by scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 48nMAssay Description:Inhibition of full-length C-terminal his-tagged human recombinant CHIT1 catalytic domain (1 to 386 residues) expressed in HEK293F cells assessed as r...More data for this Ligand-Target Pair
Affinity DataIC50: 74nMAssay Description:Inhibition of recombinant full-length C-terminal his-tagged mouse CHIT1 expressed in CHO-K1 cells assessed as reduction in chitinolytic activity usin...More data for this Ligand-Target Pair
Affinity DataIC50: 22nMAssay Description:Inhibition of full-length C-terminal his-tagged human AMCase expressed in CHO-K1 cells assessed as reduction in chitinolytic activity using 4-methylu...More data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Inhibition of full-length C-terminal his-tagged mouse AMCase expressed in expressed in CHO-K1 cells assessed as reduction in chitinolytic activity us...More data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Oncoarendi Therapeutics
Curated by ChEMBL
Oncoarendi Therapeutics
Curated by ChEMBL
Affinity DataIC50: 300nMAssay Description:Inhibition of radioligand binding to human dopamine transporter by radioligand binding assayMore data for this Ligand-Target Pair