BDBM50504629 CHEMBL4455743

SMILES NS(=O)(=O)c1ccc(N\N=C2/C(=O)N(Cc3ccccc3)c3ccc(Cl)cc23)cc1

InChI Key InChIKey=MYZKXOBWXUDLLE-UHFFFAOYSA-N

Data  4 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50504629   

TargetCarbonic anhydrase 9(Human)
Egyptian Russian University

Curated by ChEMBL
LigandPNGBDBM50504629(CHEMBL4455743)
Affinity DataKi:  20nMAssay Description:Inhibition of recombinant human carbonic anhydrase 9 preincubated for 15 mins by phenol red dye based stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetCarbonic anhydrase 12(Human)
Egyptian Russian University

Curated by ChEMBL
LigandPNGBDBM50504629(CHEMBL4455743)
Affinity DataKi:  34nMAssay Description:Inhibition of recombinant human carbonic anhydrase 12 preincubated for 15 mins by phenol red dye based stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Egyptian Russian University

Curated by ChEMBL
LigandPNGBDBM50504629(CHEMBL4455743)
Affinity DataKi:  53nMAssay Description:Inhibition of recombinant human carbonic anhydrase 2 preincubated for 15 mins by phenol red dye based stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Egyptian Russian University

Curated by ChEMBL
LigandPNGBDBM50504629(CHEMBL4455743)
Affinity DataKi:  4.83E+3nMAssay Description:Inhibition of recombinant human carbonic anhydrase 1 preincubated for 15 mins by phenol red dye based stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Human)
Egyptian Russian University

Curated by ChEMBL
LigandPNGBDBM50504629(CHEMBL4455743)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant CDK2/Cyclin E expressed in baculovirus infected Sf9 cells using histone H1 substrate in presence of [gamma33P]ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
Egyptian Russian University

Curated by ChEMBL
LigandPNGBDBM50504629(CHEMBL4455743)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human full length N-terminal GST-HIS6 fused CDK9 (M1 to F372 residues)/N-terminal HIS6-fused Cyclin-T1 (M1 to K726 residues) co-express...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed