BDBM50505055 CHEMBL4449930

SMILES Cn1ncc(NC(=O)c2nc(sc2N)-c2c(F)cccc2F)c1N1CCC[C@@H](CC1)NCC(F)(F)F

InChI Key InChIKey=QHOGQRUUXZIZIW-LBPRGKRZSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50505055   

TargetSerine/threonine-protein kinase pim-3(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50505055(CHEMBL4449930)
Affinity DataKi:  0.0200nMAssay Description:Inhibition of recombinant human PIM3 using FAM-pimtide as substrate after 90 mins by Z-LYTE assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetSerine/threonine-protein kinase pim-1(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50505055(CHEMBL4449930)
Affinity DataKi:  0.200nMAssay Description:Inhibition of recombinant human PIM1 using FAM-pimtide as substrate after 90 mins by Z-LYTE assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetSerine/threonine-protein kinase pim-2(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50505055(CHEMBL4449930)
Affinity DataKi:  9nMAssay Description:Inhibition of recombinant human PIM2 using FAM-pimtide as substrate after 90 mins by Z-LYTE assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed