BDBM50505140 CHEMBL4526884

SMILES O=C(Nc1ccc2[nH]c(=O)oc2c1)C(=O)N1CCN(c2ccc(Cl)c(F)c2)CC1

InChI Key InChIKey=FEJPEWXUTQZTFU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50505140   

TargetGlutamate receptor ionotropic, NMDA 2B(Mouse)
Shionogi

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50505140BDBM50505140(CHEMBL4526884)
Affinity DataIC50: 1nMAssay Description:Antagonist activity at mouse NR2B receptor expressed in HEK293 cells co-expressing NR1 subunit assessed as reduction in glutamic acid/glycine-induced...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2B(Rat)
Shionogi

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50505140BDBM50505140(CHEMBL4526884)
Affinity DataIC50: 13nMAssay Description:Displacement of [3H]-ifenprodil from NR2B receptor in rat brain cerebral cortex membranes incubated for 120 mins by liquid scintillation counting met...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed