BDBM50505561 CHEMBL4475810

SMILES COC1=CC(=O)N(C(=O)/C=C/[C@H](Cc2ccccc2)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)OC(=O)[C@H](Cc2ccccc2)N(C)C)[C@H]1C

InChI Key InChIKey=INGVILAVYNKSSU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50505561   

TargetCruzipain(Trypanosoma cruzi)
The University of Jordan

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50505561BDBM50505561(CHEMBL4475810)
Affinity DataIC50: 1.20nMAssay Description:Inhibition of recombinant Trypanosoma cruzi Cruzain expressed in Pichia pastoris using Z-Phe-Arg-AMC substrate incubated for 30 mins by fluorescence ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetProcathepsin L(Human)
The University of Jordan

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50505561BDBM50505561(CHEMBL4475810)
Affinity DataIC50: 3.5nMAssay Description:Inhibition of human cathepsin L using fluorogenic substrate cbz-FR-AMC monitored for 90 to 120 mins by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed