BDBM50505565 CHEMBL4474668

SMILES CC[C@H](C)[C@@H](C(=O)O[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@H](/C=C/C(=O)N1C(=O)C=C(OC)[C@H]1Cc1ccccc1)Cc1ccccc1)N(C)C

InChI Key InChIKey=YUJAVMJKRUKNMF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50505565   

TargetCruzipain(Trypanosoma cruzi)
The University of Jordan

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50505565BDBM50505565(CHEMBL4474668)
Affinity DataIC50: 1.10nMAssay Description:Inhibition of recombinant Trypanosoma cruzi Cruzain expressed in Pichia pastoris using Z-Phe-Arg-AMC substrate incubated for 30 mins by fluorescence ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetProcathepsin L(Human)
The University of Jordan

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50505565BDBM50505565(CHEMBL4474668)
Affinity DataIC50: 1.70nMAssay Description:Inhibition of human cathepsin L using fluorogenic substrate cbz-FR-AMC monitored for 90 to 120 mins by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed