BDBM50505776 CHEMBL4454796

SMILES Cc1ccccc1NC(=O)NCC(O)=O

InChI Key InChIKey=CUQFEHKORVQEQE-UHFFFAOYSA-N

Data  4 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50505776   

TargetIntegrin alpha-V/beta-3(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50505776(CHEMBL4454796)
Affinity DataIC50: 3.40nMAssay Description:Binding affinity to alphaVbeta3 integrin receptor (unknown origin) incubated fro 30 mins by competitive solid-phase binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-3(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50505776(CHEMBL4454796)
Affinity DataEC50:  85nMAssay Description:Agonist activity at alphaVbeta3 integrin receptor in human SK-MEL-24 cells assessed as increase in fibronectin-induced cell adhesion pre-incubated fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-3(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50505776(CHEMBL4454796)
Affinity DataEC50:  299nMAssay Description:Agonist activity at alphaVbeta3 integrin receptor in human Saos-2 cells assessed as increase in fibronectin-induced cell adhesion pre-incubated for 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetIntegrin alpha-5/beta-1(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50505776(CHEMBL4454796)
Affinity DataIC50: 1.00E+3nMAssay Description:Binding affinity to alpha5beta1 integrin receptor (unknown origin) incubated fro 30 mins by competitive solid-phase binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50505776(CHEMBL4454796)
Affinity DataIC50: 1.00E+3nMAssay Description:Binding affinity to alpha4beta1 integrin receptor (unknown origin) incubated for 1 hr by scintillation proximity binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetIntegrin alpha-5/beta-1(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50505776(CHEMBL4454796)
Affinity DataIC50: 3.51E+3nMAssay Description:Antagonist activity at alpha5beta1 integrin receptor in human K562 cells assessed as reduction in fibronectin-induced cell adhesion pre-incubated for...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed