BDBM50506053 CHEMBL4562740

SMILES Cc1c(nc(-c2ccc(Cl)o2)n1-c1c(Cl)cccc1Cl)C(F)(F)F

InChI Key InChIKey=QDGOIPBUPCANLG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50506053   

TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Global Discovery Chemistry

Curated by ChEMBL
LigandPNGBDBM50506053(CHEMBL4562740)
Affinity DataIC50:  4nMAssay Description:Displacement of RIP140 cofactor peptide from human His6-tagged RORgammat LBD (264 to 518 residues) by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Global Discovery Chemistry

Curated by ChEMBL
LigandPNGBDBM50506053(CHEMBL4562740)
Affinity DataIC50:  189nMAssay Description:Inhibition of human full-length eGFP-tagged RORgammat expressed in human HUT78 T-cells assessed as inhibition of PMA/CD3 monoclonal antibody stimulat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed