BDBM50506194 CHEMBL4462656

SMILES O=C1CC(=O)N(c2cccc(c2)-c2noc(=S)[n-]2)c2ccc3ccccc3c2N1

InChI Key InChIKey=YORKBPQSPSJNHS-UHFFFAOYSA-M

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50506194   

TargetP2X purinoceptor 4(Human)
Bayer

Curated by ChEMBL
LigandPNGBDBM50506194(CHEMBL4462656)
Affinity DataIC50: 260nMAssay Description:Antagonist activity at human P2X4 receptor tranfected in human 1321N1 cells assessed as inhibition of ATP-induced calcium influx incubated for 15 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetP2X purinoceptor 4(Human)
Bayer

Curated by ChEMBL
LigandPNGBDBM50506194(CHEMBL4462656)
Affinity DataIC50: 1.35E+3nMAssay Description:Antagonist activity at human P2X4R transfected in HEK293 cells preincubated for 30 mins followed by CTP addition by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed