BDBM50506450 CHEMBL4553298

SMILES COc1cc(NC(=O)c2ccc(C)c(c2)C#Cc2cc(cnc2N)-c2cnn(C)c2)cc(OC)c1

InChI Key InChIKey=IDRXBZLEXZZNDE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50506450   

TargetMacrophage colony-stimulating factor 1 receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50506450(CHEMBL4553298)
Affinity DataIC50: 2.60nMAssay Description:Inhibition of human recombinant CSF1R using ATP/Ulight-TK peptide incubated for 15 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50506450(CHEMBL4553298)
Affinity DataIC50: 2.60nMAssay Description:Inhibition of recombinant CSF1R (unknown origin) using poly (Glu, Tyr)4:1 as substrate measured after 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed