BDBM50506458 CHEMBL4576115

SMILES Cc1ccc(cc1C#Cc1cc(cnc1N)-c1cnn(C)c1)C(=O)Nc1ccc(Cl)cc1

InChI Key InChIKey=JZKQBPWOWAPASE-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50506458   

TargetMacrophage colony-stimulating factor 1 receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50506458(CHEMBL4576115)
Affinity DataIC50:  0.700nMAssay Description:Inhibition of recombinant CSF1R (unknown origin) using poly (Glu, Tyr)4:1 as substrate measured after 1 hr by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 1(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50506458(CHEMBL4576115)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged FGFR1 (456 to 765 residues) expressed in baculovirus infected Sf21 insect cells using poly (Glu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 2(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50506458(CHEMBL4576115)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of recombinant human N-terminal His6-tagged FGFR2 (456 to 770 residues) expressed in baculovirus infected Sf21 insect cells using poly (Gl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50506458(CHEMBL4576115)
Affinity DataIC50:  0.700nMAssay Description:Inhibition of human recombinant CSF1R using ATP/Ulight-TK peptide incubated for 15 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 4(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50506458(CHEMBL4576115)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of recombinant human N-terminal His6-tagged FGFR4 (442 to 755 residues) expressed in baculovirus infected Sf21 insect cells using poly (Gl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50506458(CHEMBL4576115)
Affinity DataIC50: >4.00E+4nMAssay Description:Inhibition of human ERG by Qpatch automatic patch-clamp assaysMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 3(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50506458(CHEMBL4576115)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of recombinant human N-terminal His6-tagged FGFR3 (447 to 761 residues) expressed in baculovirus infected Sf21 insect cells using poly (Gl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed