BDBM50506491 CHEMBL4521951

SMILES CC(C)C[C@@H](CN(CC(=O)N[C@H](CN(CC(=O)N[C@@H](CCC(O)=O)CN(CC(=O)N[C@H](CN(CC(=O)N[C@@H](CCCCN)CN(CC(=O)N[C@@H](CC(C)C)CN(CC(=O)N[C@@H](C)CN(CC(N)=O)S(C)(=O)=O)S(=O)(=O)CC(C)C)S(C)(=O)=O)S(C)(=O)=O)Cc1c[nH]c2ccccc12)S(C)(=O)=O)S(C)(=O)=O)Cc1ccccc1)S(=O)(=O)c1ccc(Cl)cc1)NC(C)=O

InChI Key InChIKey=HLACHACEIOQHPF-UHFFFAOYSA-N

Data  2 IC50  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50506491   

TargetE3 ubiquitin-protein ligase Mdm2(Human)
University of South Florida

Curated by ChEMBL
LigandPNGBDBM50506491(CHEMBL4521951)
Affinity DataKd:  57nMAssay Description:Binding affinity to human MDM2 expressed in Escherichia coli expression system by using (FITC)-labeled p53 peptide based fluorescence polarization co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetProtein Mdm4(Human)
University of South Florida

Curated by ChEMBL
LigandPNGBDBM50506491(CHEMBL4521951)
Affinity DataKd:  370nMAssay Description:Binding affinity to MDMX (unknown origin) by using (FITC)-labeled p53 peptide based fluorescence polarization competitive assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
University of South Florida

Curated by ChEMBL
LigandPNGBDBM50506491(CHEMBL4521951)
Affinity DataIC50: 2.80E+3nMAssay Description:Binding affinity to human MDM2 expressed in Escherichia coli expression system by using (FITC)-labeled p53 peptide based fluorescence polarization co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetProtein Mdm4(Human)
University of South Florida

Curated by ChEMBL
LigandPNGBDBM50506491(CHEMBL4521951)
Affinity DataIC50: 6.00E+3nMAssay Description:Binding affinity to MDMX (unknown origin) by using (FITC)-labeled p53 peptide based fluorescence polarization competitive assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed