BDBM50506662 CHEMBL4483615

SMILES OC(=O)CN1C(=O)S\C(=C/c2ccc(OCCc3ccccc3)cc2)C1=O

InChI Key InChIKey=LCTXZSDGCCZQDI-ATVHPVEESA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50506662   

TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
University of Messina

Curated by ChEMBL
LigandPNGBDBM50506662(CHEMBL4483615)
Affinity DataIC50:  6.38E+4nMAssay Description:Inhibition of human full-length GST-fused PTP1B expressed in bacterial expression system using pNPP as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
University of Messina

Curated by ChEMBL
LigandPNGBDBM50506662(CHEMBL4483615)
Affinity DataIC50:  364nMAssay Description:Inhibition of human recombinant aldose reductase expressed in Escherichia coli BL21 (DE3) pLysS assessed as reduction in NADPH oxidation using L-idos...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed