BDBM50507209 CHEMBL4537101

SMILES COc1c(cc(Cl)c2[nH]ccc12)C(=O)CCC1CCN(CC2CCCCC2)CC1

InChI Key InChIKey=DUUYHLUSDHATNS-UHFFFAOYSA-N

Data  2 KI  1 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50507209   

TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Normandie Univ

Curated by ChEMBL
LigandPNGBDBM50507209(CHEMBL4537101)
Affinity DataKi:  5.10nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma-1 receptor in human Jurkat cell membranes after 2 hrs by liquid scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Normandie Univ

Curated by ChEMBL
LigandPNGBDBM50507209(CHEMBL4537101)
Affinity DataKi:  41nMAssay Description:Displacement of [3H]-GR113808 from recombinant human 5-HT4BR expressed in membranes after 60 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Normandie Univ

Curated by ChEMBL
LigandPNGBDBM50507209(CHEMBL4537101)
Affinity DataIC50:  91nMAssay Description:Inhibition of human erythrocytes AChE using acetylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition measured at ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed