BDBM50507257 CHEMBL4475116

SMILES CCCNc1ccc2C(=O)N(CCCCCC(=O)NO)C(=O)c3cccc1c23

InChI Key InChIKey=UODZPFZHXUXNPW-UHFFFAOYSA-N

Data  13 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 13 hits for monomerid = 50507257   

TargetHistone deacetylase 5(Homo sapiens (Human))
Deakin University

Curated by ChEMBL
LigandPNGBDBM50507257(CHEMBL4475116)
Affinity DataIC50:  5.30E+3nMAssay Description:Inhibition of recombinant C-terminal His-tagged human HDAC5 (656 to 1122 residues) expressed in insect cells using Boc-K(Ac)-AMC as substrate by fluo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Deakin University

Curated by ChEMBL
LigandPNGBDBM50507257(CHEMBL4475116)
Affinity DataIC50:  4.80nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human HDAC6 (1 to 1215 residues) expressed in Baculovirus infected insect cells using RHKK-Ac as subs...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPolyamine deacetylase HDAC10(Homo sapiens (Human))
Deakin University

Curated by ChEMBL
LigandPNGBDBM50507257(CHEMBL4475116)
Affinity DataIC50:  320nMAssay Description:Inhibition of human HDAC10 using RHKK-Ac as substrate by fluorimetric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Deakin University

Curated by ChEMBL
LigandPNGBDBM50507257(CHEMBL4475116)
Affinity DataIC50:  1.52E+3nMAssay Description:Inhibition of recombinant C-terminal His-tagged human HDAC8 (1 to 377 residues) expressed in Baculovirus infected insect cells using RHK-K(Ac)-AMC as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 7(Homo sapiens (Human))
Deakin University

Curated by ChEMBL
LigandPNGBDBM50507257(CHEMBL4475116)
Affinity DataIC50:  9.40E+3nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human HDAC7 (518 to 991 residues) expressed in Baculovirus infected insect cells using Boc-K(Ac)-AMC ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
Deakin University

Curated by ChEMBL
LigandPNGBDBM50507257(CHEMBL4475116)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of recombinant N-terminal GST-tagged /C-terminal His-tagged human HDAC4 (627 to 1084 residues) expressed in Baculovirus infected insect ce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Deakin University

Curated by ChEMBL
LigandPNGBDBM50507257(CHEMBL4475116)
Affinity DataIC50:  4.80nMAssay Description:Inhibition of HDAC6 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
Deakin University

Curated by ChEMBL
LigandPNGBDBM50507257(CHEMBL4475116)
Affinity DataIC50:  420nMAssay Description:Inhibition of recombinant full length C-terminal GST-tagged human HDAC2 (1 to 488 residues) expressed in insect cells using RHK-K(Ac)-AMC as substrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Deakin University

Curated by ChEMBL
LigandPNGBDBM50507257(CHEMBL4475116)
Affinity DataIC50:  590nMAssay Description:Inhibition of recombinant full length C-terminal FLAG/His-tagged human HDAC1 (1 to 482 residues) expressed in sf21 cells using RHK-K(Ac)-AMC as subst...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 11(Homo sapiens (Human))
Deakin University

Curated by ChEMBL
LigandPNGBDBM50507257(CHEMBL4475116)
Affinity DataIC50:  80nMAssay Description:Inhibition of recombinant C-terminal His-tagged human HDAC11 (1 to 347 residues) expressed in Baculovirus infected insect cells using RHKK-Ac as subs...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 9(Homo sapiens (Human))
Deakin University

Curated by ChEMBL
LigandPNGBDBM50507257(CHEMBL4475116)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human HDAC9 using Boc-Lys(trifluoroacetyl)-AMC as substrate by fluorimetric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Deakin University

Curated by ChEMBL
LigandPNGBDBM50507257(CHEMBL4475116)
Affinity DataIC50:  590nMAssay Description:Inhibition of HDAC1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)(Homo sapiens (Human))
Deakin University

Curated by ChEMBL
LigandPNGBDBM50507257(CHEMBL4475116)
Affinity DataIC50:  110nMAssay Description:Inhibition of human recombinant full length C-terminal His-tagged HDAC3 (1 to 428 residues)/N-terminal GST-tagged NCOR2 (395 to 489 residues) express...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed