BDBM50507673 CHEMBL4441650

SMILES CC(C)n1cc(nn1)-c1n[nH]c2ccnc(NC3CCOCC3)c12

InChI Key InChIKey=CFPBGXJXTBQODU-UHFFFAOYSA-N

Data  1 KI  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50507673   

TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Genentech

Curated by ChEMBL

LigandBDBM50507673(CHEMBL4441650)Copy SMILESCopy InChI

Affinity DataKi:  1.20nMAssay Description:Inhibition of recombinant human GST-tagged LRRK2 G2019S mutant catalytic domain (970 to 2527 residues) expressed in insect cells using RtGWWRFYTLRRAR...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
2/19/2021
Entry Details Article
Copy BDB DOIPubMed
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TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Genentech

Curated by ChEMBL

LigandBDBM50507673(CHEMBL4441650)Copy SMILESCopy InChI

Affinity DataIC50: 49nMAssay Description:Inhibition of LRRK2 G2019S mutant (unknown origin) by cell based assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
2/19/2021
Entry Details Article
Copy BDB DOIPubMed
Copy reaction URL