BDBM50507686 CHEMBL4437282

SMILES COc1ccc(CCn2c(=O)n(Cc3ccc(cc3)C(=O)NO)c3ccccc3c2=O)cc1

InChI Key InChIKey=BRPFEMHATQFLIK-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50507686   

TargetHistone deacetylase 6(Human)
Annji Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50507686(CHEMBL4437282)
Affinity DataIC50: 20nMAssay Description:Inhibition of human full-length recombinant HDAC6 expressed in baculovirus infected Sf9 insect cells using fluorogenic peptide RHKKAc as substrate af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
Annji Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50507686(CHEMBL4437282)
Affinity DataIC50: 1.15E+3nMAssay Description:Inhibition of human full-length recombinant HDAC8 expressed in baculovirus infected Sf9 insect cells using fluorogenic peptide RHKAcKAc as substrate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Annji Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50507686(CHEMBL4437282)
Affinity DataIC50: 7.37E+3nMAssay Description:Inhibition of human full-length recombinant HDAC1 expressed in baculovirus infected Sf9 insect cells using fluorogenic peptide RHKKAc as substrate af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetHistone deacetylase 11(Human)
Annji Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50507686(CHEMBL4437282)
Affinity DataIC50: 1.39E+4nMAssay Description:Inhibition of human full-length recombinant HDAC11 expressed in baculovirus infected Sf9 insect cells using fluorogenic peptide RHKKAc as substrate a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed