BDBM50508008 CHEMBL4438379

SMILES FC(F)(F)Oc1ccc(cc1)C(=O)N1CCC(CC1)c1ncnc2cc(cnc12)N1CCOCC1

InChI Key InChIKey=KDKCALNNEHIURA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50508008   

TargetMitogen-activated protein kinase 7(Human)
Bayer

Curated by ChEMBL
LigandPNGBDBM50508008(CHEMBL4438379)
Affinity DataIC50:  150nMAssay Description:Inhibition of ERK5 in human SN12C cells transduced with MEF2-responsive transcription element assessed as reduction in MEF2 transcription by measurin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetMitogen-activated protein kinase 7(Human)
Bayer

Curated by ChEMBL
LigandPNGBDBM50508008(CHEMBL4438379)
Affinity DataIC50:  17nMAssay Description:Inhibition of His-tagged MAP2K5 activated N-terminal GST-tagged recombinant human ERK5 (1 to 398 residues) expressed in Escherichia coli using biotin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed