BDBM50508283 CHEMBL4591886

SMILES CCOCCOc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2cc1NC(=O)\C=C\CN(CC)CC

InChI Key InChIKey=CYQSRZQWLBOOCC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50508283   

TargetEpidermal growth factor receptor(Human)
Arromax Pharmatech

Curated by ChEMBL
LigandPNGBDBM50508283(CHEMBL4591886)
Affinity DataIC50: 1.5nMAssay Description:Inhibition of recombinant human GST-tagged EGFR catalytic domain (668 to 1210 residues) expressed in baculovirus expression system using TK-biotin pe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Arromax Pharmatech

Curated by ChEMBL
LigandPNGBDBM50508283(CHEMBL4591886)
Affinity DataIC50: 11nMAssay Description:Inhibition of recombinant human His-tagged HER2 catalytic domain (676 to 1255 residues) expressed in baculovirus expression system using TK-biotin pe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed