BDBM50509146 CHEMBL4303275

SMILES CCn1c(N)c(C(=O)NC)c(=O)c2ccc(nc12)C#C[C@@](C)(O)COC

InChI Key InChIKey=PFMPOBVAYMTUOX-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50509146   

TargetVascular endothelial growth factor receptor 3(Human)
Korea University

Curated by ChEMBL
LigandPNGBDBM50509146(CHEMBL4303275)
Affinity DataIC50: 1.20nMAssay Description:Inhibition of human VEGFR3 using poly[Glu:Tyr] (4:1) substrate and [gamma-33P]-ATP by radiometric biochemical kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Korea University

Curated by ChEMBL
LigandPNGBDBM50509146(CHEMBL4303275)
Affinity DataIC50: 67nMAssay Description:Inhibition of human VEGFR2 using poly[Glu:Tyr] (4:1) substrate and [gamma-33P]-ATP by radiometric biochemical kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Korea University

Curated by ChEMBL
LigandPNGBDBM50509146(CHEMBL4303275)
Affinity DataIC50: 290nMAssay Description:Inhibition of human FLT3 using EAIYAAPFAKKK substrate and [gamma-33P]-ATP by radiometric biochemical kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed