BDBM50509379 CHEMBL4439480

SMILES [H][C@]12[C@H](CC(C)C)NC(=O)[C@@]11[C@]([H])(C=C(CO)[C@H]2C)[C@]2([H])[C@]3(CC[C@]1(O)O3)CCC[C@@]2(C)O

InChI Key InChIKey=QATSZQQBBVIJIU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50509379   

TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Human)
Huazhong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50509379(CHEMBL4439480)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of IDH1 R132H mutant (unknown origin) assessed as reduction in NADPH consumption using alpha-KG as substrate incubated for 5 mins followed...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed