BDBM50509511 CHEMBL4457798

SMILES OC(=O)C(F)(F)F.OC(=O)C(F)(F)F.CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](N)CCCNC(=N)NC(=O)NCCCCNC(=O)CCCCCN1\C(=C\C=C\C=C\C2=[N+](CCCCS([O-])(=O)=O)c3ccccc3C2(C)C)C(C)(C)c2cc(ccc12)S(O)(=O)=O)C(=O)N[C@@H](CC(C)C)C(O)=O

InChI Key InChIKey=GCOJNVSSODRPBC-LZUDCTEISA-N

Data  3 KI  3 Kd  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50509511   

TargetNeurotensin receptor type 1(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50509511(CHEMBL4457798)
Affinity DataKi:  1.30nMAssay Description:Displacement of [3H] UR-MK300 from human neurotensin receptor 1 stably expressed in CHO cells incubated in dark after 30 mins by liquid scintillation...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetNeurotensin receptor type 1(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50509511(CHEMBL4457798)
Affinity DataKi:  1.40nMAssay Description:Displacement of [3H] UR-MK300 from human neurotensin receptor 1 expressed in HT-29 cells incubated in dark after 30 mins by liquid scintillation coun...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetNeurotensin receptor type 2(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50509511(CHEMBL4457798)
Affinity DataKi:  4nMAssay Description:Displacement of [3H] UR-MK300 from human neurotensin receptor 2 in HEK293 cells homogenate incubated in dark after 30 mins by liquid scintillation co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetNeurotensin receptor type 1(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50509511(CHEMBL4457798)
Affinity DataEC50:  5.90nMAssay Description:Agonist activity at human neurotensin receptor 1 in HT-29 cells assessed as intracellular calcium mobilization by Fura-2 dye based spectrofluorimetry...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetNeurotensin receptor type 1(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50509511(CHEMBL4457798)
Affinity DataKd:  3.80nMAssay Description:Binding affinity to human neurotensin receptor 1 stably expressed in CHO cells incubated for 75 mins in presence of NT (8 to 13) followed by compound...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetNeurotensin receptor type 1(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50509511(CHEMBL4457798)
Affinity DataEC50:  0.417nMAssay Description:Agonist activity at human neurotensin receptor 1 expressed in CHO cells assessed as increase in intracellular calcium by Fluo-4 dye based fluorescenc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetNeurotensin receptor type 1(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50509511(CHEMBL4457798)
Affinity DataKd:  3.90nMAssay Description:Binding affinity to human neurotensin receptor 1 stably expressed in CHO cells preincubated for 20 mins to 2 hrs followed by addition of NT (8 to 13)...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetNeurotensin receptor type 1(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50509511(CHEMBL4457798)
Affinity DataKd:  6.30nMAssay Description:Binding affinity to human neurotensin receptor 1 stably expressed in CHO cells incubated for 60 mins in presence of NT (8 to 13) without compound was...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed