BDBM50509818 CHEMBL4579221

SMILES COc1cccc(NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](Cc2ccc3ccccc3c2)NC(=O)c2cc3cc(Cl)ccc3[nH]2)c1

InChI Key InChIKey=GGYYSTJFHOEGEK-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50509818   

TargetCatenin beta-1 (138-781), Transcription Factor 4 (7-51), and Cadherin-1 (819-873)(Human)
H. Lee Moffitt Cancer Center and Research Institute

US Patent
LigandPNGBDBM50509818(CHEMBL4579221 | US20250289848, Example 33)
Affinity DataKi:  2.40E+3nMAssay Description:Experiments were performed in 96-well Microfluor 2 black plates on a Synergy 2 plate reader (Biotek). The polarization was measured at room temperatu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2026
Entry Details
US Patent

TargetCatenin beta-1(Human)
H. Lee Moffitt Cancer Center and Research Institute

Curated by ChEMBL
LigandPNGBDBM50509818(CHEMBL4579221 | US20250289848, Example 33)
Affinity DataKi:  2.40E+3nMAssay Description:Inhibition of C-terminal fluorescein-labeled human TCF4 (7 to 51 residues) binding to wild-type C-terminal His6-tagged beta-catenin (138 to 781 resid...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetCatenin beta-1(Human)
H. Lee Moffitt Cancer Center and Research Institute

Curated by ChEMBL
LigandPNGBDBM50509818(CHEMBL4579221 | US20250289848, Example 33)
Affinity DataIC50: 9.30E+3nMAssay Description:Inhibition of C-terminal fluorescein-labeled human TCF4 (7 to 51 residues) binding to wild-type C-terminal His6-tagged beta-catenin (138 to 781 resid...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed