BDBM50510183 CHEMBL4457634

SMILES CN1CCOc2c1cnn1c(nnc21)-c1ccc2cc(Cl)cc(NCC3(F)CCNCC3)c2n1

InChI Key InChIKey=SGUNCNYHPYXQNG-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50510183   

TargetSerine/threonine-protein kinase pim-3(Human)
Spanish National Cancer Research Centre (Cnio)

Curated by ChEMBL
LigandPNGBDBM50510183(CHEMBL4457634)
Affinity DataIC50: 1nMAssay Description:Inhibition of N-terminal 6-His tagged human recombinant PIM3 using PIM tide (ARKRRRHPSGPPTA) as substrate incubated for 1 hr by fluorescence based as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase pim-1(Human)
Spanish National Cancer Research Centre (Cnio)

Curated by ChEMBL
LigandPNGBDBM50510183(CHEMBL4457634)
Affinity DataIC50: 30nMAssay Description:Inhibition of His tagged human recombinant PIM1 using PIM tide (ARKRRRHPSGPPTA) as substrate incubated for 1 hr by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase pim-2(Human)
Spanish National Cancer Research Centre (Cnio)

Curated by ChEMBL
LigandPNGBDBM50510183(CHEMBL4457634)
Affinity DataIC50: 1.27E+3nMAssay Description:Inhibition of His tagged human recombinant PIM2 using PIM tide (ARKRRRHPSGPPTA) as substrate incubated for 1 hr by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed