BDBM50510273 CHEMBL4583532

SMILES Cc1cnc(Nc2ccccc2)nc1-c1cc2CN(CCc2o1)C(=O)CC#N

InChI Key InChIKey=LDNZJTDKNJMMLC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50510273   

TargetTyrosine-protein kinase JAK2(Human)
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50510273(CHEMBL4583532)
Affinity DataIC50: 2.90nMAssay Description:Inhibition of JAK2 (unknown origin) using TK-substrate-biotin as substrate preincubated for 5 mins followed by substrate addition and measured by 30 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50510273(CHEMBL4583532)
Affinity DataIC50: 95nMAssay Description:Inhibition of JAK3 (unknown origin) using TK-substrate-biotin as substrate preincubated for 5 mins followed by substrate addition and measured by 30 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed