BDBM50510274 CHEMBL4464597

SMILES CCC(=O)N1CCc2oc(cc2C1)-c1nc(Nc2ccc(cc2)N2CCOCC2)ncc1C

InChI Key InChIKey=XDKHOBQYXVWWCR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50510274   

TargetTyrosine-protein kinase JAK2(Human)
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50510274(CHEMBL4464597)
Affinity DataIC50: 5.80nMAssay Description:Inhibition of JAK2 (unknown origin) using TK-substrate-biotin as substrate preincubated for 5 mins followed by substrate addition and measured by 30 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50510274(CHEMBL4464597)
Affinity DataIC50: 112nMAssay Description:Inhibition of JAK3 (unknown origin) using TK-substrate-biotin as substrate preincubated for 5 mins followed by substrate addition and measured by 30 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed