BDBM50510756 CHEMBL4447664

SMILES [H][C@]12C[C@@]3([H])C4=CCO[C@@]5([H])[C@H](N)C(=O)N6c7ccccc7[C@@]1(CCN2C4)[C@]6([H])[C@@]35[H]

InChI Key InChIKey=XHGQHKSZUGARHU-UHFFFAOYSA-N

Data  1 KI  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50510756   

TargetGlycine receptor subunit alpha-1(Human)
The German University In Cairo

Curated by ChEMBL
LigandPNGBDBM50510756(CHEMBL4447664)
Affinity DataIC50: 194nMAssay Description:Antagonist activity at human glycine receptor subunit alpha-1 expressed in HEK293 cells assessed as reduction in glycine-induced whole cell currents ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetGlycine receptor subunit alpha-1(Human)
The German University In Cairo

Curated by ChEMBL
LigandPNGBDBM50510756(CHEMBL4447664)
Affinity DataKi:  741nMAssay Description:Displacement of [3H]strychnine from human glycine receptor subunit alpha-1 expressed in HEK293 cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetGlycine receptor subunit alpha-1(Human)
The German University In Cairo

Curated by ChEMBL
LigandPNGBDBM50510756(CHEMBL4447664)
Affinity DataIC50: 1.00E+3nMAssay Description:Antagonist activity at human glycine receptor subunit alpha-1 expressed in human tsA201 cells assessed as reduction in glycine-induced response by fl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetGlycine receptor subunit alpha-1(Human)
The German University In Cairo

Curated by ChEMBL
LigandPNGBDBM50510756(CHEMBL4447664)
Affinity DataIC50: 1.00E+3nMAssay Description:Antagonist activity at human glycine receptor subunit alpha-1 expressed in human tsA201 cells assessed as reduction in glycine-induced response by fl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetGlycine receptor subunit alpha-1/beta(Human)
The German University In Cairo

Curated by ChEMBL
LigandPNGBDBM50510756(CHEMBL4447664)
Affinity DataIC50: 7.70E+3nMAssay Description:Antagonist activity at human glycine receptor subunit alpha-1beta expressed in human tsA201 cells assessed as reduction in glycine-induced response b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetGlycine receptor subunit alpha-1/beta(Human)
The German University In Cairo

Curated by ChEMBL
LigandPNGBDBM50510756(CHEMBL4447664)
Affinity DataIC50: 7.76E+3nMAssay Description:Antagonist activity at human glycine receptor subunit alpha-1beta expressed in human tsA201 cells assessed as reduction in glycine-induced response b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed