BDBM50511198 CHEMBL4564731

SMILES OC(=O)c1cccc(NCc2ccc(OCc3ccc(F)cc3)cc2)c1

InChI Key InChIKey=QZRQQAJDHIPRHE-UHFFFAOYSA-N

Data  1 Kd  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50511198   

TargetPeroxisome proliferator-activated receptor alpha(Human)
University of Oklahoma

Curated by ChEMBL
LigandPNGBDBM50511198(CHEMBL4564731)
Affinity DataEC50:  770nMAssay Description:Agonist activity at human PPARalpha expressed in nonhuman mammalian cells assessed as increase in receptor transcriptional activity incubated for 22 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
University of Oklahoma

Curated by ChEMBL
LigandPNGBDBM50511198(CHEMBL4564731)
Affinity DataKd:  5.32E+3nMAssay Description:Binding affinity to His-tagged PPARalpha LBD (unknown origin) expressed in Escherichia coli Rosetta (DE3) at 25 degree C by isothermal titration calo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor delta(Human)
University of Oklahoma

Curated by ChEMBL
LigandPNGBDBM50511198(CHEMBL4564731)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at human PPARdelta expressed in nonhuman mammalian cells assessed as increase in receptor transcriptional activity incubated for 22 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
University of Oklahoma

Curated by ChEMBL
LigandPNGBDBM50511198(CHEMBL4564731)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at human PPARgamma expressed in nonhuman mammalian cells assessed as increase in receptor transcriptional activity incubated for 22 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed